Michaela Agapiou |
BBSRC DTP studentship
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Project |
Michaela is a PhD student studying how an RNA binding protein, held out wings, regulates translation during spermatogenesis in D. melanogaster. Using a variety of techniques to understand both the mechanism and physiological role of HOW, such as, ribo-seq, X-ray crystallography and sperm competition assays.
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Background |
Michaela worked previously on Drosophila during a computational project assessing the expression of clustered miRNAs during D. melanogaster and D. virilis development at the University of Manchester. She has also carried out placements at Thomas Jefferson University (Philadelphia, USA) and the MRC London Institute of Medical Sciences on topics including: autophagy, macrophage motility and angiogenesis.
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Education
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2016-Present ‘Dissecting the mechanisms of translational regulation in Drosophila germ stem cells’
Supervised by Dr Julie Aspden, Dr Amanda Bretman and Dr Thomas Edwards 2012-2016 BSc Biochemistry with Professional Experience, University of Manchester |
Research interests |
RNA binding proteins and translation, germ cell development, specialised ribosomes.
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Technical skills |
Drosophila genetics and husbandry, cloning, protein expression, electron microscopy grid preparation, confocal microscopy, Western blotting, RIP-seq, ribo-seq and a working knowledge of Python.
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